Genome-wide association study of Stevens-Johnson Syndrome and Toxic Epidermal Necrolysis in Europe.
Génin E, Schumacher M, Roujeau JC et al.
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Abstract
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Stevens-Johnson syndrome (SJS) and Toxic Epidermal Necrolysis (TEN) are rare but extremely severe cutaneous adverse drug reactions in which drug-specific associations with HLA-B alleles were described.
424 European ancestry cases, 1,881 European ancestry controls
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