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GWAS Study

A genome wide association study (GWAS) providing evidence of an association between common genetic variants and late radiotherapy toxicity.

Barnett GC, Thompson D, Fachal L et al.

24785509 PubMed ID
GWAS Study Type
3506 Participants
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Chapter I

Publication Details

Comprehensive information about this research publication

Authors

BG
Barnett GC
TD
Thompson D
FL
Fachal L
KS
Kerns S
TC
Talbot C
ER
Elliott RM
DL
Dorling L
CC
Coles CE
DD
Dearnaley DP
RB
Rosenstein BS
VA
Vega A
SP
Symonds P
YJ
Yarnold J
BC
Baynes C
MK
Michailidou K
DJ
Dennis J
TJ
Tyrer JP
WJ
Wilkinson JS
GA
Gómez-Caamaño A
TG
Tanteles GA
PR
Platte R
MR
Mayes R
CD
Conroy D
MM
Maranian M
LC
Luccarini C
GS
Gulliford SL
SM
Sydes MR
HE
Hall E
HJ
Haviland J
MV
Misra V
TJ
Titley J
BS
Bentzen SM
PP
Pharoah PD
BN
Burnet NG
DA
Dunning AM
WC
West CM
Chapter II

Abstract

Summary of the research findings

Background and purpose: This study was designed to identify common single nucleotide polymorphisms (SNPs) associated with toxicity 2years after radiotherapy.

579 European ancestry prostate cancer cases, 1,194 European ancestry breast cancer cases

Chapter III

Study Statistics

Key metrics and study information

3506
Total Participants
GWAS
Study Type
Yes
Replicated
516 European ancestry prostate cancer cases, 862 prostate cancer cases, 355 breast cancer cases
Replication Participants
European
Ancestry
Spain, U.S., U.K.
Recruitment Country
Chapter IV

AI-Generated Summary

AI-generated by DNAGENICS

Independent AI summary of health and genetic findings from the published study

Important: This summary is AI-generated by DNAGENICS for informational purposes only. It was not created by, affiliated with, or endorsed by the researchers behind the original publication, and is based solely on that published research. It may contain errors or omissions. DNAGENICS disclaims all liability for any inaccuracies or consequences arising from use of this information. Verify all information against the original publication. This is not professional scientific review or medical advice.

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