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GWAS Study

Genome-wide association study of height-adjusted BMI in childhood identifies functional variant in ADCY3.

Stergiakouli E, Gaillard R, Tavaré JM et al.

25044758 PubMed ID
GWAS Study Type
7898 Participants
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Chapter I

Publication Details

Comprehensive information about this research publication

Authors

SE
Stergiakouli E
GR
Gaillard R
TJ
Tavaré JM
BN
Balthasar N
LR
Loos RJ
TH
Taal HR
ED
Evans DM
RF
Rivadeneira F
SP
St Pourcain B
UA
Uitterlinden AG
KJ
Kemp JP
HA
Hofman A
RS
Ring SM
CT
Cole TJ
JV
Jaddoe VW
DS
Davey Smith G
TN
Timpson NJ
Chapter II

Abstract

Summary of the research findings

Objective: Genome-wide association studies (GWAS) of BMI are mostly undertaken under the assumption that "kg/m(2) " is an index of weight fully adjusted for height, but in general this is not true. The aim here was to assess the contribution of common genetic variation to a adjusted version of that phenotype which appropriately accounts for covariation in height in children.

5,809 children

Chapter III

Study Statistics

Key metrics and study information

7898
Total Participants
GWAS
Study Type
Yes
Replicated
2,089 European ancestry children
Replication Participants
European
Ancestry
U.K., Netherlands
Recruitment Country
Chapter IV

AI-Generated Summary

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