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GWAS Study

Electronic medical records and genomics (eMERGE) network exploration in cataract: several new potential susceptibility loci.

Ritchie MD, Verma SS, Hall MA et al.

25352737 PubMed ID
GWAS Study Type
7397 Participants
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Chapter I

Publication Details

Comprehensive information about this research publication

Authors

RM
Ritchie MD
VS
Verma SS
HM
Hall MA
GR
Goodloe RJ
BR
Berg RL
CD
Carrell DS
CC
Carlson CS
CL
Chen L
CD
Crosslin DR
DJ
Denny JC
JG
Jarvik G
LR
Li R
LJ
Linneman JG
PJ
Pathak J
PP
Peissig P
RL
Rasmussen LV
RA
Ramirez AH
WX
Wang X
WR
Wilke RA
WW
Wolf WA
TE
Torstenson ES
TS
Turner SD
MC
McCarty CA
Chapter II

Abstract

Summary of the research findings

Purpose: Cataract is the leading cause of blindness in the world, and in the United States accounts for approximately 60% of Medicare costs related to vision. The purpose of this study was to identify genetic markers for age-related cataract through a genome-wide association study (GWAS).

5,503 European, Black, and other ancestry cases age 50 and older, 1,894 European, Black, and other ancestry controls age 50 and older

Chapter III

Study Statistics

Key metrics and study information

7397
Total Participants
GWAS
Study Type
No
Replicated
African unspecified, Other, European
Ancestry
U.S.
Recruitment Country
Chapter IV

AI-Generated Summary

AI-generated by DNAGENICS

Independent AI summary of health and genetic findings from the published study

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