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GWAS Study

A rapid functional decline type of amyotrophic lateral sclerosis is linked to low expression of TTN.

Watanabe H, Atsuta N, Hirakawa A et al.

26746183 PubMed ID
GWAS Study Type
465 Participants
43 Views
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Chapter I

Publication Details

Comprehensive information about this research publication

Authors

WH
Watanabe H
AN
Atsuta N
HA
Hirakawa A
NR
Nakamura R
NM
Nakatochi M
IS
Ishigaki S
IA
Iida A
IS
Ikegawa S
KM
Kubo M
YD
Yokoi D
WH
Watanabe H
IM
Ito M
KM
Katsuno M
IY
Izumi Y
MM
Morita M
KK
Kanai K
TA
Taniguchi A
AI
Aiba I
AK
Abe K
MK
Mizoguchi K
OM
Oda M
KO
Kano O
OK
Okamoto K
KS
Kuwabara S
HK
Hasegawa K
IT
Imai T
KA
Kawata A
AM
Aoki M
TS
Tsuji S
NK
Nakashima K
KR
Kaji R
SG
Sobue G
Chapter II

Abstract

Summary of the research findings

Objective: To classify the patterns of functional decline in patients with sporadic amyotrophic lateral sclerosis (ALS) and explore the genetic backgrounds that modified these patterns.

59 Japanese ancestry cases with rapid functional decline, 110 Japanese ancestry cases with intermediate functional decline, 70 Japanese ancestry cases with sigmoidal functional decline, 215 Japanese ancestry cases with moderate functional decline

Chapter III

Study Statistics

Key metrics and study information

465
Total Participants
GWAS
Study Type
No
Replicated
East Asian
Ancestry
Japan
Recruitment Country
Chapter IV

AI-Generated Summary

AI-generated by DNAGENICS

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