Genetic Associations with Obstructive Sleep Apnea Traits in Hispanic/Latino Americans.
Cade BE, Chen H, Stilp AM et al.
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Abstract
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Rationale: Obstructive sleep apnea is a common disorder associated with increased risk for cardiovascular disease, diabetes, and premature mortality. Although there is strong clinical and epidemiologic evidence supporting the importance of genetic factors in influencing obstructive sleep apnea, its genetic basis is still largely unknown. Prior genetic studies focused on traits defined using the apnea-hypopnea index, which contains limited information on potentially important genetically determined physiologic factors, such as propensity for hypoxemia and respiratory arousability.
12,558 Hispanic/Latin American individuals
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