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GWAS Study

Rare coding variants associated with blood pressure variation in 15 914 individuals of African ancestry.

Nandakumar P, Lee D, Richard MA et al.

28234671 PubMed ID
GWAS Study Type
15914 Participants
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Chapter I

Publication Details

Comprehensive information about this research publication

Authors

NP
Nandakumar P
LD
Lee D
RM
Richard MA
TF
Tekola-Ayele F
TB
Tayo BO
WE
Ware E
SY
Sung YJ
SB
Salako B
OA
Ogunniyi A
GC
Gu CC
GM
Grove ML
FM
Fornage M
KS
Kardia S
RC
Rotimi C
CR
Cooper RS
MA
Morrison AC
EG
Ehret G
CA
Chakravarti A
Chapter II

Abstract

Summary of the research findings

Objectives: Hypertension is a major risk factor for all cardiovascular diseases, especially among African Americans. This study focuses on identifying specific blood pressure (BP) genes using 15 914 individuals of African ancestry from eight cohorts (Africa America Diabetes Mellitus, Atherosclerosis Risk in Communities Study, Coronary Artery Risk Development in young Adults, Genetics Network, Genetic Epidemiology Network of Arteriopathy, Howard University Family Study, Hypertension Genetic Epidemiology Network, and Loyola University Chicago Cohort) to further genetic findings in this population which has generally been underrepresented in BP studies.

11,156 African American individuals, 4,758 African ancestry individuals

Chapter III

Study Statistics

Key metrics and study information

15914
Total Participants
GWAS
Study Type
No
Replicated
Sub-Saharan African, African American or Afro-Caribbean
Ancestry
Ghana, Nigeria, U.S.
Recruitment Country
Chapter IV

AI-Generated Summary

AI-generated by DNAGENICS

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