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GWAS Study

Red blood cell distribution width: Genetic evidence for aging pathways in 116,666 volunteers.

Pilling LC, Atkins JL, Duff MO et al.

28957414 PubMed ID
GWAS Study Type
116666 Participants
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Chapter I

Publication Details

Comprehensive information about this research publication

Authors

PL
Pilling LC
AJ
Atkins JL
DM
Duff MO
BR
Beaumont RN
JS
Jones SE
TJ
Tyrrell J
KC
Kuo CL
RK
Ruth KS
TM
Tuke MA
YH
Yaghootkar H
WA
Wood AR
MA
Murray A
WM
Weedon MN
HL
Harries LW
KG
Kuchel GA
FL
Ferrucci L
FT
Frayling TM
MD
Melzer D
Chapter II

Abstract

Summary of the research findings

Introduction: Variability in red blood cell volumes (distribution width, RDW) increases with age and is strongly predictive of mortality, incident coronary heart disease and cancer. We investigated inherited genetic variation associated with RDW in 116,666 UK Biobank human volunteers.

116,666 British ancestry individuals

Chapter III

Study Statistics

Key metrics and study information

116666
Total Participants
GWAS
Study Type
No
Replicated
European
Ancestry
Chapter IV

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