Maternal and fetal genetic contribution to gestational weight gain.
Warrington NM, Richmond R, Fenstra B et al.
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Abstract
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Clinical recommendations to limit gestational weight gain (GWG) imply high GWG is causally related to adverse outcomes in mother or offspring, but GWG is the sum of several inter-related complex phenotypes (maternal fat deposition and vascular expansion, placenta, amniotic fluid and fetal growth). Understanding the genetic contribution to GWG could help clarify the potential effect of its different components on maternal and offspring health. Here we explore the genetic contribution to total, early and late GWG.
up to 8,559 European ancestry fetuses
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