Menu
Currency
GWAS Study

Genome-Wide Association Study Implicates Atrial Natriuretic Peptide Rather Than B-Type Natriuretic Peptide in the Regulation of Blood Pressure in the General Population.

Salo PP, Havulinna AS, Tukiainen T et al.

29237677 PubMed ID
GWAS Study Type
6305 Participants
43 Views
Scroll to explore
Chapter I

Publication Details

Comprehensive information about this research publication

Authors

SP
Salo PP
HA
Havulinna AS
TT
Tukiainen T
RO
Raitakari O
LT
Lehtimäki T
KM
Kähönen M
KJ
Kettunen J
MM
Männikkö M
EJ
Eriksson JG
JA
Jula A
BS
Blankenberg S
ZT
Zeller T
SV
Salomaa V
KK
Kristiansson K
PM
Perola M
Chapter II

Abstract

Summary of the research findings

Cardiomyocytes secrete atrial natriuretic peptide (ANP) and B-type natriuretic peptide (BNP) in response to mechanical stretching, making them useful clinical biomarkers of cardiac stress. Both human and animal studies indicate a role for ANP as a regulator of blood pressure with conflicting results for BNP.

4,932 Finnish ancestry individuals

Chapter III

Study Statistics

Key metrics and study information

6305
Total Participants
GWAS
Study Type
Yes
Replicated
1,373 Finnish ancestry individuals
Replication Participants
European
Ancestry
Finland
Recruitment Country
Chapter IV

AI-Generated Summary

AI-generated by DNAGENICS

Independent AI summary of health and genetic findings from the published study

Important: This summary is AI-generated by DNAGENICS for informational purposes only. It was not created by, affiliated with, or endorsed by the researchers behind the original publication, and is based solely on that published research. It may contain errors or omissions. DNAGENICS disclaims all liability for any inaccuracies or consequences arising from use of this information. Verify all information against the original publication. This is not professional scientific review or medical advice.

AI Summary In Progress

Our AI-generated summary of this publication is being prepared. Please check back soon.