Novel Loci Associated With Attention-Deficit/Hyperactivity Disorder Are Revealed by Leveraging Polygenic Overlap With Educational Attainment.
Shadrin AA, Smeland OB, Zayats T et al.
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Objective: Attention-deficit/hyperactivity disorder (ADHD) is a common and highly heritable psychiatric condition. By exploiting the reported relationship between ADHD and educational attainment (EA), we aimed to improve discovery of ADHD-associated genetic variants and to investigate genetic overlap between these phenotypes.
2,064 European and unknown ancestry ADHD trios, 896 European and unknown ancestry ADHD cases, 2,455 European and unknown ancestry controls, 328,917 European ancestry individuals with educational attainment data
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