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GWAS Study

Novel risk genes identified in a genome-wide association study for coronary artery disease in patients with type 1 diabetes.

Charmet R, Duffy S, Keshavarzi S et al.

29695241 PubMed ID
GWAS Study Type
6754 Participants
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Chapter I

Publication Details

Comprehensive information about this research publication

Authors

CR
Charmet R
DS
Duffy S
KS
Keshavarzi S
GB
Gyorgy B
MM
Marre M
RP
Rossing P
MA
McKnight AJ
MA
Maxwell AP
AT
Ahluwalia TVS
PA
Paterson AD
TD
Trégouët DA
HS
Hadjadj S
Chapter II

Abstract

Summary of the research findings

Patients with type 1 diabetes are more at risk of coronary artery disease than the general population. Although evidence points to a genetic risk there have been no study investigating genetic risk factors of coronary artery disease specific to individuals with type 1 diabetes. To identify low frequency and common genetic variations associated with coronary artery disease in populations of individuals with type 1 diabetes.

434 European ancestry cases with coronary artery disease, 3,123 European ancestry cases without coronary artery disease

Chapter III

Study Statistics

Key metrics and study information

6754
Total Participants
GWAS
Study Type
Yes
Replicated
585 cases with coronary artery disease, 2,612 cases without coronary artery disease
Replication Participants
European
Ancestry
U.S., France, Denmark, U.K.
Recruitment Country
Chapter IV

AI-Generated Summary

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