Role of the Complement System in Chronic Central Serous Chorioretinopathy: A Genome-Wide Association Study.
Schellevis RL, van Dijk EHC, Breukink MB et al.
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Importance: To date, several targeted genetic studies on chronic central serous chorioretinopathy (cCSC) have been performed; however, unbiased genome-wide studies into the genetics of cCSC have not been reported. To discover new genetic loci associated with cCSC and to better understand the causative mechanism of this disease, we performed a genome-wide association study (GWAS) on patients with cCSC.
521 European ancestry cases, 3,577 European ancestry controls
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