Menu
Currency
GWAS Study

Genetic Markers of ADHD-Related Variations in Intracranial Volume.

Klein M, Walters RK, Demontis D et al.

30818988 PubMed ID
GWAS Study Type
80078 Participants
36 Views
Scroll to explore
Chapter I

Publication Details

Comprehensive information about this research publication

Authors

KM
Klein M
WR
Walters RK
DD
Demontis D
SJ
Stein JL
HD
Hibar DP
AH
Adams HH
BJ
Bralten J
RM
Roth Mota N
SR
Schachar R
SE
Sonuga-Barke E
MM
Mattheisen M
NB
Neale BM
TP
Thompson PM
MS
Medland SE
BA
Børglum AD
FS
Faraone SV
AA
Arias-Vasquez A
FB
Franke B
Chapter II

Abstract

Summary of the research findings

Objective: Attention deficit hyperactivity disorder (ADHD) is a common and highly heritable neurodevelopmental disorder with a complex pathophysiology. Intracranial volume (ICV) and volumes of the nucleus accumbens, amygdala, caudate nucleus, hippocampus, and putamen are smaller in people with ADHD compared with healthy individuals. The authors investigated the overlap between common genetic variation associated with ADHD risk and these brain volume measures to identify underlying biological processes contributing to the disorder.

19,099 European ancestry ADHD cases, 1,084 ADHD cases, 34,194 European ancestry controls, 997 controls, 24,704 European ancestry individuals

Chapter III

Study Statistics

Key metrics and study information

80078
Total Participants
GWAS
Study Type
No
Replicated
European
Ancestry
Chapter IV

AI-Generated Summary

AI-generated by DNAGENICS

Independent AI summary of health and genetic findings from the published study

Important: This summary is AI-generated by DNAGENICS for informational purposes only. It was not created by, affiliated with, or endorsed by the researchers behind the original publication, and is based solely on that published research. It may contain errors or omissions. DNAGENICS disclaims all liability for any inaccuracies or consequences arising from use of this information. Verify all information against the original publication. This is not professional scientific review or medical advice.

AI Summary In Progress

Our AI-generated summary of this publication is being prepared. Please check back soon.