Menu
Currency
GWAS Study

Parkinson's disease age at onset genome-wide association study: Defining heritability, genetic loci, and α-synuclein mechanisms.

Blauwendraat C, Heilbron K, Vallerga CL et al.

30957308 PubMed ID
GWAS Study Type
28568 Participants
105 Views
Scroll to explore
Chapter I

Publication Details

Comprehensive information about this research publication

Authors

BC
Blauwendraat C
HK
Heilbron K
VC
Vallerga CL
BS
Bandres-Ciga S
VC
von Coelln R
PL
Pihlstrøm L
SJ
Simón-Sánchez J
SC
Schulte C
SM
Sharma M
KL
Krohn L
SA
Siitonen A
IH
Iwaki H
LH
Leonard H
NA
Noyce AJ
TM
Tan M
GJ
Gibbs JR
HD
Hernandez DG
SS
Scholz SW
JJ
Jankovic J
SL
Shulman LM
LS
Lesage S
CJ
Corvol JC
BA
Brice A
VH
van Hilten JJ
MJ
Marinus J
EJ
Eerola-Rautio J
TP
Tienari P
MK
Majamaa K
TM
Toft M
GD
Grosset DG
GT
Gasser T
HP
Heutink P
SJ
Shulman JM
WN
Wood N
HJ
Hardy J
MH
Morris HR
HD
Hinds DA
GJ
Gratten J
VP
Visscher PM
GZ
Gan-Or Z
NM
Nalls MA
SA
Singleton AB
Chapter II

Abstract

Summary of the research findings

Increasing evidence supports an extensive and complex genetic contribution to PD. Previous genome-wide association studies (GWAS) have shed light on the genetic basis of risk for this disease. However, the genetic determinants of PD age at onset are largely unknown.

17,996 cases

Chapter III

Study Statistics

Key metrics and study information

28568
Total Participants
GWAS
Study Type
Yes
Replicated
10,572 cases
Replication Participants
Chapter IV

AI-Generated Summary

AI-generated by DNAGENICS

Independent AI summary of health and genetic findings from the published study

Important: This summary is AI-generated by DNAGENICS for informational purposes only. It was not created by, affiliated with, or endorsed by the researchers behind the original publication, and is based solely on that published research. It may contain errors or omissions. DNAGENICS disclaims all liability for any inaccuracies or consequences arising from use of this information. Verify all information against the original publication. This is not professional scientific review or medical advice.

AI Summary In Progress

Our AI-generated summary of this publication is being prepared. Please check back soon.