Genome-wide association study identifies genetic susceptibility loci and pathways of radiation-induced acute oral mucositis.
Yang DW, Wang TM, Zhang JB et al.
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Abstract
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Radiation-induced oral mucositis (OM) is one of the most common acute complications for head and neck cancer. Severe OM is associated with radiation treatment breaks, which harms successful tumor management. Radiogenomics studies have indicated that genetic variants are associated with adverse effects of radiotherapy.
349 East Asian ancestry cases, 1,118 East Asian ancestry treated controls
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