Genome-Wide Association Study of Suicide Death and Polygenic Prediction of Clinical Antecedents.
Docherty AR, Shabalin AA, DiBlasi E et al.
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Objective: Death by suicide is a highly preventable yet growing worldwide health crisis. To date, there has been a lack of adequately powered genomic studies of suicide, with no sizable suicide death cohorts available for analysis. To address this limitation, the authors conducted the first comprehensive genomic analysis of suicide death using previously unpublished genotype data from a large population-ascertained cohort.
3,413 European ancestry cases, 14,810 European ancestry controls
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