Genetic Risk Score Constructed from Common Genetic Variants is Associated with Cardiovascular Disease Risk in Type 2 Diabetes Mellitus.
Cheng CF, Lin YJ, Lin MC et al.
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Abstract
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Patients with type 2 diabetes mellitus (T2DM) experience a two-fold increased risk of cardiovascular diseases. Genome-wide association studies (GWAS) have identified T2DM susceptibility genetic variants. Interestingly, the genetic variants associated with cardiovascular disease risk in T2DM Han Chinese remain to be elucidated. The present study aimed to investigate the genetic variants associated with cardiovascular disease risk in T2DM.
326 Han Chinese ancestry cases, 1,209 Han Chinese ancestry controls
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