A multilayered post-GWAS assessment on genetic susceptibility to pancreatic cancer.
López de Maturana E, Rodríguez JA, Alonso L et al.
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Abstract
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Pancreatic cancer (PC) is a complex disease in which both non-genetic and genetic factors interplay. To date, 40 GWAS hits have been associated with PC risk in individuals of European descent, explaining 4.1% of the phenotypic variance.
1,317 European ancestry cases, 700 European ancestry controls
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