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GWAS Study

Genetic Modifiers of Age at Onset for Parkinson's Disease in Asians: A Genome-Wide Association Study.

Li C, Ou R, Chen Y et al.

33884653 PubMed ID
GWAS Study Type
4946 Participants
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Chapter I

Publication Details

Comprehensive information about this research publication

Authors

LC
Li C
OR
Ou R
CY
Chen Y
GX
Gu X
WQ
Wei Q
CB
Cao B
ZL
Zhang L
HY
Hou Y
LK
Liu K
CX
Chen X
SW
Song W
ZB
Zhao B
WY
Wu Y
LT
Li T
DX
Dong X
SH
Shang H
Chapter II

Abstract

Summary of the research findings

Age at onset (AAO) is an essential feature of Parkinson's disease (PD) and can help predict disease progression and mortality. Identification of genetic variants influencing AAO of PD could lead to a better understanding of the disease's biological mechanism and provide clinical guidance. However, genetic determinants for AAO of PD remain mostly unknown, especially in the Asian population.

3,456 Chinese ancestry individuals

Chapter III

Study Statistics

Key metrics and study information

4946
Total Participants
GWAS
Study Type
Yes
Replicated
1,490 Chinese ancestry individuals
Replication Participants
East Asian
Ancestry
China
Recruitment Country
Chapter IV

AI-Generated Summary

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