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GWAS Study

Association analysis of juvenile idiopathic arthritis genetic susceptibility factors in Estonian patients.

Nikopensius T, Niibo P, Haller T et al.

34101054 PubMed ID
GWAS Study Type
7219 Participants
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Chapter I

Publication Details

Comprehensive information about this research publication

Authors

NT
Nikopensius T
NP
Niibo P
HT
Haller T
JT
Jagomägi T
Voog-Oras Ü
TN
Tõnisson N
MA
Metspalu A
SM
Saag M
PC
Pruunsild C
Chapter II

Abstract

Summary of the research findings

Juvenile idiopathic arthritis (JIA) is the most common chronic rheumatic condition of childhood. Genetic association studies have revealed several JIA susceptibility loci with the strongest effect size observed in the human leukocyte antigen (HLA) region. Genome-wide association studies have augmented the number of JIA-associated loci, particularly for non-HLA genes. The aim of this study was to identify new associations at non-HLA loci predisposing to the risk of JIA development in Estonian patients.

263 Estonian ancestry cases, 6,956 Estonian ancestry controls

Chapter III

Study Statistics

Key metrics and study information

7219
Total Participants
GWAS
Study Type
No
Replicated
Estonia
Recruitment Country
Chapter IV

AI-Generated Summary

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