Uniting biobank resources reveals novel genetic pathways modulating susceptibility for atopic dermatitis.
Sliz E, Huilaja L, Pasanen A et al.
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Abstract
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Atopic dermatitis (AD) is a common chronic inflammatory skin disease with high heritability. Previous genome-wide association studies have identified several loci predisposing to AD. These findings explain approximately 30% of the variance in AD susceptibility, suggesting that further work is required to fully understand the genetic underpinnings.
22,474 European ancestry cases, 774,187 European ancestry controls
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