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GWAS Study

Genome-Wide Association Study of Peripheral Artery Disease.

van Zuydam NR, Stiby A, Abdalla M et al.

34601942 PubMed ID
GWAS Study Type
727992 Participants
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Chapter I

Publication Details

Comprehensive information about this research publication

Authors

VZ
van Zuydam NR
SA
Stiby A
AM
Abdalla M
AE
Austin E
DE
Dahlström EH
MS
McLachlan S
VE
Vlachopoulou E
AE
Ahlqvist E
DL
Di Liao C
SN
Sandholm N
FC
Forsblom C
MA
Mahajan A
RN
Robertson NR
RN
Rayner NW
LE
Lindholm E
SJ
Sinisalo J
PM
Perola M
KM
Kallio M
WE
Weiss E
PJ
Price J
PA
Paterson A
KB
Klein B
SV
Salomaa V
PC
Palmer CNA
GP
Groop PH
GL
Groop L
MM
McCarthy MI
DA
de Andrade M
MA
Morris AP
HJ
Hopewell JC
CH
Colhoun HM
KI
Kullo IJ
Chapter II

Abstract

Summary of the research findings

Peripheral artery disease (PAD) affects >200 million people worldwide and is associated with high mortality and morbidity. We sought to identify genomic variants associated with PAD overall and in the contexts of diabetes and smoking status.

12,086 European ancestry cases, 449,548 European ancestry controls

Chapter III

Study Statistics

Key metrics and study information

727992
Total Participants
GWAS
Study Type
Yes
Replicated
31,307 cases, 211,753 controls, 3,164 East Asian ancestry cases, 20,134 East Asian ancestry controls
Replication Participants
European, East Asian
Ancestry
Canada, Sweden, U.S., Finland, U.K., Iceland
Recruitment Country
Chapter IV

AI-Generated Summary

AI-generated by DNAGENICS

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