Zinc finger protein 33B demonstrates sex-interaction with atopy-related markers in childhood asthma.
Lee S, Prokopenko D, Kelly RS et al.
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Abstract
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Sex differences related to immune responses can influence atopic manifestations in childhood asthma. While genome-wide association studies have investigated a sex-specific genetic architecture of the immune response, gene-by-sex interactions have not been extensively analysed for atopy-related markers including allergy skin tests, IgE and eosinophils in asthmatic children.
28 African ancestry trios, 216 European ancestry trios, 907 Hispanic trios, 22 trios
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