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Evidence of Novel Susceptibility Variants for Prostate Cancer and a Multiancestry Polygenic Risk Score Associated with Aggressive Disease in Men of African Ancestry.

Chen F, Madduri RK, Rodriguez AA et al.

36872133 PubMed ID
GWAS Study Type
80998 Participants
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Chapter I

Publication Details

Comprehensive information about this research publication

Authors

CF
Chen F
MR
Madduri RK
RA
Rodriguez AA
DB
Darst BF
CA
Chou A
SX
Sheng X
WA
Wang A
SJ
Shen J
SE
Saunders EJ
RS
Rhie SK
BJ
Bensen JT
IS
Ingles SA
KR
Kittles RA
SS
Strom SS
RB
Rybicki BA
NB
Nemesure B
IW
Isaacs WB
SJ
Stanford JL
ZW
Zheng W
SM
Sanderson M
JE
John EM
PJ
Park JY
XJ
Xu J
WY
Wang Y
BS
Berndt SI
HC
Huff CD
YE
Yeboah ED
TY
Tettey Y
LJ
Lachance J
TW
Tang W
RC
Rentsch CT
CK
Cho K
MB
Mcmahon BH
BR
Biritwum RB
AA
Adjei AA
TE
Tay E
TA
Truelove A
NS
Niwa S
ST
Sellers TA
YK
Yamoah K
MA
Murphy AB
CD
Crawford DC
PA
Patel AV
BW
Bush WS
AM
Aldrich MC
CO
Cussenot O
PG
Petrovics G
CJ
Cullen J
NC
Neslund-Dudas CM
SM
Stern MC
KZ
Kote-Jarai Z
GK
Govindasami K
CM
Cook MB
CA
Chokkalingam AP
HA
Hsing AW
GP
Goodman PJ
HT
Hoffmann TJ
DB
Drake BF
HJ
Hu JJ
KJ
Keaton JM
HJ
Hellwege JN
CP
Clark PE
JM
Jalloh M
GS
Gueye SM
NL
Niang L
OO
Ogunbiyi O
IM
Idowu MO
PO
Popoola O
AA
Adebiyi AO
AO
Aisuodionoe-Shadrach OI
AH
Ajibola HO
JM
Jamda MA
OO
Oluwole OP
NM
Nwegbu M
AB
Adusei B
MS
Mante S
DA
Darkwa-Abrahams A
MJ
Mensah JE
DH
Diop H
VD
Van Den Eeden SK
BP
Blanchet P
FJ
Fowke JH
CG
Casey G
HA
Hennis AJ
LA
Lubwama A
TI
Thompson IM
LR
Leach R
ED
Easton DF
PM
Preuss MH
LR
Loos RJ
GS
Gundell SM
WP
Wan P
MJ
Mohler JL
FE
Fontham ET
SG
Smith GJ
TJ
Taylor JA
SS
Srivastava S
ER
Eeles RA
CJ
Carpten JD
KA
Kibel AS
ML
Multigner L
PM
Parent MÉ
MF
Menegaux F
CG
Cancel-Tassin G
KE
Klein EA
AC
Andrews C
RT
Rebbeck TR
BL
Brureau L
AS
Ambs S
ET
Edwards TL
WS
Watya S
CS
Chanock SJ
WJ
Witte JS
BW
Blot WJ
MG
Michael Gaziano J
JA
Justice AC
CD
Conti DV
HC
Haiman CA
Chapter II

Abstract

Summary of the research findings

Genetic factors play an important role in prostate cancer (PCa) susceptibility.

19,378 African ancestry men cases, 61,620 African ancestry men controls

Chapter III

Study Statistics

Key metrics and study information

80998
Total Participants
GWAS
Study Type
No
Replicated
African unspecified
Ancestry
Canada, U.S., Uganda, Ghana, U.K., France, Congo
Recruitment Country
Chapter IV

AI-Generated Summary

AI-generated by DNAGENICS

Independent AI summary of health and genetic findings from the published study

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