Sex differences in the polygenic architecture of hearing problems in adults.
De Angelis F, Zeleznik OA, Wendt FR et al.
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Hearing problems (HP) in adults are common and are associated with several comorbid conditions. Its prevalence increases with age, reflecting the cumulative effect of environmental factors and genetic predisposition. Although several risk loci have been already identified, HP biology and epidemiology are still insufficiently investigated by large-scale genetic studies.
501,825 European ancestry individuals
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