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GWAS Study

Lifetime risk and genetic predisposition to post-traumatic OA of the knee in the UK Biobank.

Hollis B, Chatzigeorgiou C, Southam L et al.

37247657 PubMed ID
GWAS Study Type
3074 Participants
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Chapter I

Publication Details

Comprehensive information about this research publication

Authors

HB
Hollis B
CC
Chatzigeorgiou C
SL
Southam L
HK
Hatzikotoulas K
KS
Kluzek S
WA
Williams A
ZE
Zeggini E
JL
Jostins-Dean L
WF
Watt FE
Chapter II

Abstract

Summary of the research findings

Objective: Acute knee injury is associated with post-traumatic OA (PTOA). Very little is known about the genome-wide associations of PTOA when compared with idiopathic OA (iOA). Our objective was to describe the development of knee OA after a knee injury and its genetic associations in UK Biobank (UKB).

377 European ancestry post-injury cases, 2,697 European ancestry post-injury controls

Chapter III

Study Statistics

Key metrics and study information

3074
Total Participants
GWAS
Study Type
No
Replicated
European
Ancestry
U.K.
Recruitment Country
Chapter IV

AI-Generated Summary

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