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GWAS Study

Extended genome-wide association study employing the African genome resources panel identifies novel susceptibility loci for Alzheimer's disease in individuals of African ancestry.

Ray NR, Kunkle BW, Hamilton-Nelson K et al.

38958117 PubMed ID
GWAS Study Type
9168 Participants
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Chapter I

Publication Details

Comprehensive information about this research publication

Authors

RN
Ray NR
KB
Kunkle BW
HK
Hamilton-Nelson K
KJ
Kurup JT
RF
Rajabli F
QM
Qiao M
VB
Vardarajan BN
CM
Cosacak MI
KC
Kizil C
JM
Jean-Francois M
CM
Cuccaro M
RD
Reyes-Dumeyer D
CL
Cantwell L
KA
Kuzma A
VJ
Vance JM
GS
Gao S
HH
Hendrie HC
BO
Baiyewu O
OA
Ogunniyi A
AR
Akinyemi RO
LW
Lee WP
ME
Martin ER
WL
Wang LS
BG
Beecham GW
BW
Bush WS
XW
Xu W
JF
Jin F
WL
Wang L
FL
Farrer LA
HJ
Haines JL
BG
Byrd GS
SG
Schellenberg GD
MR
Mayeux R
PM
Pericak-Vance MA
RC
Reitz C
Chapter II

Abstract

Summary of the research findings

Introduction: Despite a two-fold risk, individuals of African ancestry have been underrepresented in Alzheimer's disease (AD) genomics efforts.

77 African ancestry cases, 628 African ancestry controls, 2,826 African American cases, 5,637 African American controls

Chapter III

Study Statistics

Key metrics and study information

9168
Total Participants
GWAS
Study Type
No
Replicated
Sub-Saharan African, African American or Afro-Caribbean
Ancestry
Nigeria, U.S.
Recruitment Country
Chapter IV

AI-Generated Summary

AI-generated by DNAGENICS

Independent AI summary of health and genetic findings from the published study

Important: This summary is AI-generated by DNAGENICS for informational purposes only. It was not created by, affiliated with, or endorsed by the researchers behind the original publication, and is based solely on that published research. It may contain errors or omissions. DNAGENICS disclaims all liability for any inaccuracies or consequences arising from use of this information. Verify all information against the original publication. This is not professional scientific review or medical advice.

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