A genome-wide association study of longitudinal change in CSF tau among non-demented elderly.
Liu Y, Zhang N, Liu S et al.
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Methods: This study conducted a genome-wide association study (GWAS) on longitudinal CSF t-tau and genotype data from 319 non-Hispanic Caucasians within the Alzheimer's Disease Neuroimaging Initiative (ADNI) cohort. The aim was to identify genetic determinants influencing the rate of change in CSF t-tau, a key biomarker in AD.
191 mildly cognitively impaired individuals, 126 cognitively normal individuals
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