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Plasma Vitamin C and Type 2 Diabetes: Genome-Wide Association Study and Mendelian Randomization Analysis in European Populations.

Zheng JS, Luan J, Sofianopoulou E et al.

33203707 PubMed ID
GWAS Study Type
52018 Participants
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Chapter I

Publication Details

Comprehensive information about this research publication

Authors

ZJ
Zheng JS
LJ
Luan J
SE
Sofianopoulou E
IF
Imamura F
SI
Stewart ID
DF
Day FR
PM
Pietzner M
WE
Wheeler E
LL
Lotta LA
GT
Gundersen TE
AP
Amiano P
AE
Ardanaz E
CM
Chirlaque MD
FG
Fagherazzi G
FP
Franks PW
KR
Kaaks R
LN
Laouali N
MF
Mancini FR
NP
Nilsson PM
ON
Onland-Moret NC
OA
Olsen A
OK
Overvad K
PS
Panico S
PD
Palli D
RF
Ricceri F
RO
Rolandsson O
SA
Spijkerman AMW
SM
Sánchez MJ
SM
Schulze MB
SN
Sala N
SS
Sieri S
TA
Tjønneland A
TR
Tumino R
VD
van der Schouw YT
WE
Weiderpass E
RE
Riboli E
DJ
Danesh J
BA
Butterworth AS
SS
Sharp SJ
LC
Langenberg C
FN
Forouhi NG
WN
Wareham NJ
Chapter II

Abstract

Summary of the research findings

Objective: Higher plasma vitamin C levels are associated with lower type 2 diabetes risk, but whether this association is causal is uncertain. To investigate this, we studied the association of genetically predicted plasma vitamin C with type 2 diabetes.

52,018 European ancestry individuals

Chapter III

Study Statistics

Key metrics and study information

52018
Total Participants
GWAS
Study Type
No
Replicated
European
Ancestry
France, Germany, Denmark, Greece, Italy, Netherlands, Norway, Spain, Sweden, U.K.
Recruitment Country
Chapter IV

AI-Generated Summary

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