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Identification of a Common Variant for Coronary Heart Disease at PDE1A Contributes to Individualized Treatment Goals and Risk Stratification of Cardiovascular Complications in Chinese Patients With Type 2 Diabetes.

Tam CHT, Lim CKP, Luk AOY et al.

37125963 PubMed ID
GWAS Study Type
17534 Participants
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Chapter I

Publication Details

Comprehensive information about this research publication

Authors

TC
Tam CHT
LC
Lim CKP
LA
Luk AOY
SM
Shi M
MC
Man Cheung H
NA
Ng ACW
LH
Lee HM
LE
Lau ESH
FB
Fan B
JG
Jiang G
KA
Kong APS
OR
Ozaki R
CE
Chow EYK
LK
Lee KF
SS
Siu SC
HG
Hui G
TC
Tsang CC
LK
Lau KP
LJ
Leung JYY
CE
Cheung EYN
TM
Tsang MW
KG
Kam G
LI
Lau IT
LJ
Li JKY
YV
Yeung VTF
LE
Lau E
LS
Lo S
FS
Fung S
CY
Cheng YL
CC
Chow CC
FX
Fan X
CT
Chan TF
YK
Yip KYL
LS
Lok S
YW
Yu W
TS
Tsui SKW
LH
Lan HY
SC
Szeto CC
TN
Tang NLS
TB
Tomlinson B
HY
Huang Y
JA
Jenkins AJ
KA
Keech A
SW
So WY
CJ
Chan JCN
MR
Ma RCW
Chapter II

Abstract

Summary of the research findings

Objective: In this study we aim to unravel genetic determinants of coronary heart disease (CHD) in type 2 diabetes (T2D) and explore their applications.

2,517 Southern Han Chinese ancestry cases, 6,424 Southern Han Chinese ancestry controls

Chapter III

Study Statistics

Key metrics and study information

17534
Total Participants
GWAS
Study Type
Yes
Replicated
1,079 Southern Han Chinese ancestry cases, 2,474 Southern Han Chinese ancestry controls, 764 European ancestry cases, 4,276 European ancestry controls
Replication Participants
East Asian, European
Ancestry
China, Hong Kong SAR, New Zealand, Finland, Australia
Recruitment Country
Chapter IV

AI-Generated Summary

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