Genome-wide association of sleep and circadian phenotypes.
Gottlieb DJ, O'Connor GT, Wilk JB
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Abstract
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Numerous studies suggest genetic influences on sleepiness and circadian rhythms. The Sleep Heart Health Study collected questionnaire data on sleep habits and sleepiness from 2848 Framingham Heart Study Offspring Cohort participants. More than 700 participants were genotyped using the Affymetrix 100K SNP GeneChip, providing a unique opportunity to assess genetic linkage and association of these traits.
up to 738 individuals from 203 families
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