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GWAS Study

Genetics of coronary artery calcification among African Americans, a meta-analysis.

Wojczynski MK, Li M, Bielak LF et al.

23870195 PubMed ID
GWAS Study Type
15815 Participants
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Chapter I

Publication Details

Comprehensive information about this research publication

Authors

WM
Wojczynski MK
LM
Li M
BL
Bielak LF
KK
Kerr KF
RA
Reiner AP
WN
Wong ND
YL
Yanek LR
QL
Qu L
WC
White CC
LL
Lange LA
FJ
Ferguson JF
HJ
He J
YT
Young T
MT
Mosley TH
SJ
Smith JA
KB
Kral BG
GX
Guo X
WQ
Wong Q
GS
Ganesh SK
HS
Heckbert SR
GM
Griswold ME
OD
O'Leary DH
BM
Budoff M
CJ
Carr JJ
TH
Taylor HA
BD
Bluemke DA
DS
Demissie S
HS
Hwang SJ
PD
Paltoo DN
PJ
Polak JF
PB
Psaty BM
BD
Becker DM
PM
Province MA
PW
Post WS
OC
O'Donnell CJ
WJ
Wilson JG
HT
Harris TB
KM
Kavousi M
CL
Cupples LA
RJ
Rotter JI
FM
Fornage M
BL
Becker LC
PP
Peyser PA
BI
Borecki IB
RM
Reilly MP
Chapter II

Abstract

Summary of the research findings

Coronary heart disease (CHD) is the major cause of death in the United States. Coronary artery calcification (CAC) scores are independent predictors of CHD. African Americans (AA) have higher rates of CHD but are less well-studied in genomic studies. We assembled the largest AA data resource currently available with measured CAC to identify associated genetic variants.

5,823 African American individuals

Chapter III

Study Statistics

Key metrics and study information

15815
Total Participants
GWAS
Study Type
Yes
Replicated
9,992 European ancestry individuals
Replication Participants
European, African American or Afro-Caribbean
Ancestry
U.S.
Recruitment Country
Chapter IV

AI-Generated Summary

AI-generated by DNAGENICS

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