Meta-analysis of genome-wide association studies for circulating phylloquinone concentrations.
Dashti HS, Shea MK, Smith CE et al.
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Poor vitamin K status is linked to greater risk of several chronic diseases. Age, sex, and diet are determinants of circulating vitamin K; however, there is still large unexplained interindividual variability in vitamin K status. Although a strong genetic component has been hypothesized, this has yet to be examined by a genome-wide association (GWA) study.
2,138 European ancestry individuals
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