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PROX1 gene CC genotype as a major determinant of early onset of type 2 diabetes in slavic study participants from Action in Diabetes and Vascular Disease: Preterax and Diamicron MR Controlled Evaluation study.

Hamet P, Haloui M, Harvey F et al.

28060188 PubMed ID
GWAS Study Type
3409 Participants
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Chapter I

Publication Details

Comprehensive information about this research publication

Authors

HP
Hamet P
HM
Haloui M
HF
Harvey F
MF
Marois-Blanchet FC
SM
Sylvestre MP
TM
Tahir MR
SP
Simon PH
KB
Kanzki BS
RJ
Raelson J
LC
Long C
CJ
Chalmers J
WM
Woodward M
MM
Marre M
HS
Harrap S
TJ
Tremblay J
Chapter II

Abstract

Summary of the research findings

The prevalence of diabetic nephropathy varies according to ethnicity. Environmental as well as genetic factors contribute to the heterogeneity in the presentation of diabetic nephropathy. Our objective was to evaluate this heterogeneity within the Caucasian population.

2,307 Celtic ancestry individuals, 1,102 Slavic ancestry individuals

Chapter III

Study Statistics

Key metrics and study information

3409
Total Participants
GWAS
Study Type
No
Replicated
European
Ancestry
Poland, Czech Republic, Australia, Italy, Russian Federation, Netherlands, Canada, Germany, U.K., Estonia, Hungary, New Zealand, Slovakia, Lithuania, France, Republic of Ireland
Recruitment Country
Chapter IV

AI-Generated Summary

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