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Twenty-Five Novel Loci for Carotid Intima-Media Thickness: A Genome-Wide Association Study in >45 000 Individuals and Meta-Analysis of >100 000 Individuals.

Yeung MW, Wang S, van de Vegte YJ et al.

34852643 PubMed ID
GWAS Study Type
45185 Participants
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Chapter I

Publication Details

Comprehensive information about this research publication

Authors

YM
Yeung MW
WS
Wang S
VD
van de Vegte YJ
BO
Borisov O
VS
van Setten J
SH
Snieder H
VN
Verweij N
SM
Said MA
VD
van der Harst P
Chapter II

Abstract

Summary of the research findings

Objective: Carotid artery intima-media thickness (cIMT) is a widely accepted marker of subclinical atherosclerosis. Twenty susceptibility loci for cIMT were previously identified and the identification of additional susceptibility loci furthers our knowledge on the genetic architecture underlying atherosclerosis.

43,775 European ancestry individuals, 612 Asian ancestry individuals, 291 Black individuals, 215 Mixed ancestry individuals, 292 individuals

Chapter III

Study Statistics

Key metrics and study information

45185
Total Participants
GWAS
Study Type
No
Replicated
European, Asian unspecified, African unspecified, Other admixed ancestry
Ancestry
U.K.
Recruitment Country
Chapter IV

AI-Generated Summary

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