Perinatal depression is associated with a higher polygenic risk for major depressive disorder than non-perinatal depression.
Kiewa J, Meltzer-Brody S, Milgrom J et al.
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Abstract
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Distinctions between major depressive disorder (MDD) and perinatal depression (PND) reflect varying views of PND, from a unique etiological subtype of MDD to an MDD episode that happens to coincide with childbirth. This case-control study investigated genetic differences between PND and MDD outside the perinatal period (non-perinatal depression or NPD).
3,804 European ancestry cases, 6,134 European ancestry controls
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