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GWAS Study

A genome-wide association study of outcome from traumatic brain injury.

Kals M, Kunzmann K, Parodi L et al.

35301180 PubMed ID
GWAS Study Type
4710 Participants
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Chapter I

Publication Details

Comprehensive information about this research publication

Authors

KM
Kals M
KK
Kunzmann K
PL
Parodi L
RF
Radmanesh F
WL
Wilson L
IS
Izzy S
AC
Anderson CD
PA
Puccio AM
OD
Okonkwo DO
TN
Temkin N
SE
Steyerberg EW
SM
Stein MB
MG
Manley GT
MA
Maas AIR
RS
Richardson S
DR
Diaz-Arrastia R
PA
Palotie A
RS
Ripatti S
RJ
Rosand J
MD
Menon DK
Chapter II

Abstract

Summary of the research findings

Factors such as age, pre-injury health, and injury severity, account for less than 35% of outcome variability in traumatic brain injury (TBI). While some residual outcome variability may be attributable to genetic factors, published candidate gene association studies have often been underpowered and subject to publication bias.

2,509 European ancestry cases, 2,201 European ancestry controls

Chapter III

Study Statistics

Key metrics and study information

4710
Total Participants
GWAS
Study Type
No
Replicated
European, African unspecified, Other admixed ancestry
Ancestry
U.S., Finland, U.K.
Recruitment Country
Chapter IV

AI-Generated Summary

AI-generated by DNAGENICS

Independent AI summary of health and genetic findings from the published study

Important: This summary is AI-generated by DNAGENICS for informational purposes only. It was not created by, affiliated with, or endorsed by the researchers behind the original publication, and is based solely on that published research. It may contain errors or omissions. DNAGENICS disclaims all liability for any inaccuracies or consequences arising from use of this information. Verify all information against the original publication. This is not professional scientific review or medical advice.

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