Polygenic inheritance and its interplay with smoking history in predicting lung cancer diagnosis: a French-Canadian case-control cohort.
Boumtje V, Manikpurage HD, Li Z et al.
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Abstract
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The most near-term clinical application of genome-wide association studies in lung cancer is a polygenic risk score (PRS).
4,002 French-Canadian ancestry cases, 20,010 French-Canadian ancestry controls
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