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GWAS Study

Genome-wide association meta-analysis of 88,250 individuals highlights pleiotropic mechanisms of five ocular diseases in UK Biobank.

Xue Z, Yuan J, Chen F et al.

35841873 PubMed ID
GWAS Study Type
66387 Participants
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Chapter I

Publication Details

Comprehensive information about this research publication

Authors

XZ
Xue Z
YJ
Yuan J
CF
Chen F
YY
Yao Y
XS
Xing S
YX
Yu X
LK
Li K
WC
Wang C
BJ
Bao J
QJ
Qu J
SJ
Su J
CH
Chen H
Chapter II

Abstract

Summary of the research findings

Ocular diseases may exhibit common clinical symptoms and epidemiological comorbidity. However, the extent of pleiotropic mechanisms across ocular diseases remains unclear. We aim to examine shared genetic etiology in age-related macular degeneration (AMD), diabetic retinopathy (DR), glaucoma, retinal detachment (RD), and myopia.

5,873 European ancestry cases, 60,514 European ancestry controls

Chapter III

Study Statistics

Key metrics and study information

66387
Total Participants
GWAS
Study Type
No
Replicated
European
Ancestry
U.K.
Recruitment Country
Chapter IV

AI-Generated Summary

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