Genome-wide analysis of oxylipins and oxylipin profiles in a pediatric population.
Buckner T, Johnson RK, Vanderlinden LA et al.
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Oxylipins are inflammatory biomarkers derived from omega-3 and-6 fatty acids implicated in inflammatory diseases but have not been studied in a genome-wide association study (GWAS). The aim of this study was to identify genetic loci associated with oxylipins and oxylipin profiles to identify biologic pathways and therapeutic targets for oxylipins.
253 European ancestry children at risk of type 1 diabetes, 63 children at risk of type 1 diabetes
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