Genome-wide association study of chronic sputum production implicates loci involved in mucus production and infection.
Packer RJ, Shrine N, Hall R et al.
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Abstract
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Chronic sputum production impacts on quality of life and is a feature of many respiratory diseases. Identification of the genetic variants associated with chronic sputum production in a disease agnostic sample could improve understanding of its causes and identify new molecular targets for treatment.
9,714 European ancestry cases, 48,471 European ancestry controls
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