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GWAS Study

Genetic Variants Associated With Hidradenitis Suppurativa.

Sun Q, Broadaway KA, Edmiston SN et al.

37494057 PubMed ID
GWAS Study Type
834662 Participants
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Chapter I

Publication Details

Comprehensive information about this research publication

Authors

SQ
Sun Q
BK
Broadaway KA
ES
Edmiston SN
FK
Fajgenbaum K
MT
Miller-Fleming T
WL
Westerkam LL
MM
Melendez-Gonzalez M
BH
Bui H
BF
Blum FR
LB
Levitt B
LL
Lin L
HH
Hao H
HK
Harris KM
LZ
Liu Z
TN
Thomas NE
CN
Cox NJ
LY
Li Y
MK
Mohlke KL
SC
Sayed CJ
Chapter II

Abstract

Summary of the research findings

Importance: Hidradenitis suppurativa (HS) is a common and severely morbid chronic inflammatory skin disease that is reported to be highly heritable. However, the genetic understanding of HS is insufficient, and limited genome-wide association studies (GWASs) have been performed for HS, which have not identified significant risk loci.

1,640 European ancestry, African American or Afro-Caribbean, NR cases, 756,393 European ancestry, African American or Afro-Caribbean, NR controls

Chapter III

Study Statistics

Key metrics and study information

834662
Total Participants
GWAS
Study Type
Yes
Replicated
189 European ancestry cases, 64,234 European ancestry controls, 101 African American or Afro-Caribbean cases, 12,105 African American or Afro-Caribbean controls
Replication Participants
European, African American or Afro-Caribbean, NR, European, African American or Afro-Caribbean
Ancestry
U.S., Finland, U.K.
Recruitment Country
Chapter IV

AI-Generated Summary

AI-generated by DNAGENICS

Independent AI summary of health and genetic findings from the published study

Important: This summary is AI-generated by DNAGENICS for informational purposes only. It was not created by, affiliated with, or endorsed by the researchers behind the original publication, and is based solely on that published research. It may contain errors or omissions. DNAGENICS disclaims all liability for any inaccuracies or consequences arising from use of this information. Verify all information against the original publication. This is not professional scientific review or medical advice.

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