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Epistasis of ERAP1 With 4 Major Histocompatibility Complex Class I Alleles in Frontal Fibrosing Alopecia: A Genome-Wide Association Study Meta-Analysis.

Rayinda T, Dand N, McSweeney SM et al.

39937552 PubMed ID
GWAS Study Type
6668 Participants
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Chapter I

Publication Details

Comprehensive information about this research publication

Authors

RT
Rayinda T
DN
Dand N
MS
McSweeney SM
CE
Christou E
UC
Ung CY
SC
Stefanato CM
FD
Fenton DA
HM
Harries M
PI
Palamaras I
TA
Tidman A
HS
Holmes S
KA
Koutalopoulou A
AM
Ardern-Jones M
KM
Kaur M
PS
Papanikou S
CV
Chasapi V
VS
Vañó-Galvan S
SD
Saceda-Corralo D
MA
Melián-Olivera A
AC
Azcarraga-Llobet C
LA
Lobato-Berezo A
BM
Bustamante M
SJ
Sunyer J
SM
Starace MVR
PB
Piraccini BM
WI
Wiss IP
SM
Senna MM
SR
Singh R
HK
Hillmann K
KV
Kanti-Schmidt V
BU
Blume-Peytavi U
MJ
McGrath JA
SM
Simpson MA
TC
Tziotzios C
Chapter II

Abstract

Summary of the research findings

Importance: Frontal fibrosing alopecia (FFA) is an inflammatory and scarring form of hair loss of increasing prevalence that most commonly affects women. An improved understanding of the genetic basis of FFA will support the identification of pathogenic mechanisms and therapeutic targets.

1,585 European ancestry female cases, 5,083 European ancestry female controls

Chapter III

Study Statistics

Key metrics and study information

6668
Total Participants
GWAS
Study Type
No
Replicated
European
Ancestry
U.K., Spain
Recruitment Country
Chapter IV

AI-Generated Summary

AI-generated by DNAGENICS

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