Limited contribution of common genetic variants to risk for liver injury due to a variety of drugs.
Urban TJ, Shen Y, Stolz A et al.
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Background and aims: Drug-induced liver injury (DILI) is a serious adverse drug event that is suspected to have a heritable component. We carried out a genome-wide association study of 783 individuals of European ancestry who experienced DILI due to more than 200 implicated drugs.
783 European ancestry cases, 3,001 European ancestry controls
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