Genome-Wide Association Studies and Meta-Analyses for Congenital Heart Defects.
Agopian AJ, Goldmuntz E, Hakonarson H et al.
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Abstract
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Maternal and inherited (ie, case) genetic factors likely contribute to the pathogenesis of congenital heart defects, but it is unclear whether individual common variants confer a large risk.
483 European ancestry trios, 406 European ancestry cases, 2,976 European ancestry controls, 355 European and other ancestry trios, 187 non-European ancestry trios.
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