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GWAS Study

Genome-wide association study of heavy smoking and daily/nondaily smoking in the Hispanic Community Health Study / Study of Latinos (HCHS/SOL).

Saccone NL, Emery LS, Sofer T et al.

28520984 PubMed ID
GWAS Study Type
5804 Participants
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Chapter I

Publication Details

Comprehensive information about this research publication

Authors

SN
Saccone NL
EL
Emery LS
ST
Sofer T
GS
Gogarten SM
BD
Becker DM
BE
Bottinger EP
CL
Chen LS
CR
Culverhouse RC
DW
Duan W
HD
Hancock DB
HH
Hosgood HD
JE
Johnson EO
LR
Loos RJF
LT
Louie T
PG
Papanicolaou G
PK
Perreira KM
RE
Rodriquez EJ
SC
Schurmann C
SA
Stilp AM
SA
Szpiro AA
TG
Talavera GA
TK
Taylor KD
TJ
Thrasher JF
YL
Yanek LR
LC
Laurie CC
PE
Pérez-Stable EJ
BL
Bierut LJ
KR
Kaplan RC
Chapter II

Abstract

Summary of the research findings

Introduction: Genetic variants associated with nicotine dependence have previously been identified, primarily in European-ancestry populations. No genome-wide association studies (GWAS) have been reported for smoking behaviors in Hispanics/Latinos in the United States and Latin America, who are of mixed ancestry with European, African, and American Indigenous components.

778 Hispanic non-daily smoker cases, 1,786 Hispanic daily smoker controls

Chapter III

Study Statistics

Key metrics and study information

5804
Total Participants
GWAS
Study Type
Yes
Replicated
85 Hispanic non-daily smokers, 343 Hispanic daily smokers, 158 African American non-daily smokers, 1,106 African American daily smokers, 232 European ancestry non-daily smokers, 1,316 European ancestry daily smokers
Replication Participants
Hispanic or Latin American, African American or Afro-Caribbean, European
Ancestry
U.S.
Recruitment Country
Chapter IV

AI-Generated Summary

AI-generated by DNAGENICS

Independent AI summary of health and genetic findings from the published study

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